Article
A Generalized Linear Model for Decomposing Cis-regulatory, Parent-of-Origin, and Maternal Effects on Allele-Specific Gene Expression.
G3 (Bethesda, Md.) - 5 Jul 2017
Takada Yasuaki, Miyagi Ryutaro, Takahashi Aya, Endo Toshinori, Osada Naoki
Abstract excerpt
Joint quantification of genetic and epigenetic effects on gene expression is important for understanding the establishment of complex gene regulation systems in living organisms. In particular, genomic imprinting and maternal effects play important roles in the developmental process of mammals and flowering plants. However, the influence of these effects on gene expression are difficult to quantify because they...
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