Article
Using next-generation RNA sequencing to identify imprinted genes.
Heredity - 1 Aug 2014
Wang X, Clark A G
Abstract excerpt
Genomic imprinting is manifested as differential allelic expression (DAE) depending on the parent-of-origin. The most direct way to identify imprinted genes is to directly score the DAE in a context where one can identify which parent transmitted each allele. Because many genes display DAE, simply scoring DAE in an individual is not sufficient to identify imprinted genes. In this paper, we outline many technical...
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