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Article

Testcrosses are an efficient strategy for identifying cis-regulatory variation: Bayesian analysis of allele-specific expression (BayesASE).

G3 (Bethesda, Md.) - 7 May 2021

Miller Brecca R, Morse Alison M, Borgert Jacqueline E, Liu Zihao, Sinclair Kelsey, Gamble Gavin, Zou Fei, Newman Jeremy R B, León-Novelo Luis G, Marroni Fabio, McIntyre Lauren M

Abstract excerpt

Allelic imbalance (AI) occurs when alleles in a diploid individual are differentially expressed and indicates cis acting regulatory variation. What is the distribution of allelic effects in a natural population? Are all alleles the same? Are all alleles distinct? The approach described applies to any technology generating allele-specific sequence counts, for example for chromatin accessibility and can be applied...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33772539
DOI: 10.1093/g3journal/jkab096
PMCID: PMC8104932

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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