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Article

The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis.

Nature communications - 13 Nov 2019

Lewandowski Jordan P, Lee James C, Hwang Taeyoung, Sunwoo Hongjae, Goldstein Jill M, Groff Abigail F, Chang Nydia P, Mallard William, Williams Adam, Henao-Meija Jorge, Flavell Richard A, Lee Jeannie T, Gerhardinger Chiara, Wagers Amy J, Rinn John L

Abstract excerpt

RNA has been classically known to play central roles in biology, including maintaining telomeres, protein synthesis, and in sex chromosome compensation. While thousands of long noncoding RNAs (lncRNAs) have been identified, attributing RNA-based roles to lncRNA loci requires assessing whether phenotype(s) could be due to DNA regulatory elements, transcription, or the lncRNA. Here, we use the conserved X...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31723143
DOI: 10.1038/s41467-019-12970-4
PMCID: PMC6853988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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