Article
The phenotype of cancer cell invasion controlled by fibril diameter and pore size of 3D collagen networks.
Biomaterials - 1 Jun 2015
Sapudom Jiranuwat, Rubner Stefan, Martin Steve, Kurth Tony, Riedel Stefanie, Mierke Claudia T, Pompe Tilo
Abstract excerpt
The behavior of cancer cells is strongly influenced by the properties of extracellular microenvironments, including topology, mechanics and composition. As topological and mechanical properties of the extracellular matrix are hard to access and control for in-depth studies of underlying mechanisms in vivo, defined biomimetic in vitro models are needed. Herein we show, how pore size and fibril diameter of collagen...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
