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Article

Conditional Reprogramming for Patient-Derived Cancer Models and Next-Generation Living Biobanks

27 Oct 2019

Abstract excerpt

Traditional cancer models including cell lines and animal models have limited applications in both basic and clinical cancer research. Genomics-based precision oncology only help 2–20% patients with solid cancer. Functional diagnostics and patient-derived cancer models are needed for precision cancer biology. In this review, we will summarize applications of conditional cell reprogramming (CR) in cancer research...

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PMID: 31717887
DOI: 10.3390/cells8111327

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