Conditionally reprogrammed normal and primary tumor prostate epithelial cells: a novel patient-derived cell model for studies of human prostate cancer.

doi:10.18632/oncotarget.13937

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Article

Conditionally reprogrammed normal and primary tumor prostate epithelial cells: a novel patient-derived cell model for studies of human prostate cancer.

Oncotarget - 4 Apr 2017

Timofeeva Olga A, Palechor-Ceron Nancy, Li Guanglei, Yuan Hang, Krawczyk Ewa, Zhong Xiaogang, Liu Geng, Upadhyay Geeta, Dakic Aleksandra, Yu Songtao, Fang Shuang, Choudhury Sujata, Zhang Xueping, Ju Andrew, Lee Myeong-Seon, Dan Han C, Ji Youngmi, Hou Yong, Zheng Yun-Ling, Albanese Chris, Rhim Johng, Schlegel Richard, Dritschilo Anatoly, Liu Xuefeng

Abstract excerpt

Our previous study demonstrated that conditional reprogramming (CR) allows the establishment of patient-derived normal and tumor epithelial cell cultures from a variety of tissue types including breast, lung, colon and prostate. Using CR, we have established matched normal and tumor cultures, GUMC-29 and GUMC-30 respectively, from a patient's prostatectomy specimen. These CR cells proliferate indefinitely in...

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PMID: 28009986
DOI: 10.18632/oncotarget.13937
PMCID: PMC5410259

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