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Article

Novel genetic variants in HDAC2 and PPARGC1A of the CREB-binding protein pathway predict survival of non-small-cell lung cancer.

Molecular carcinogenesis - 1 Jan 2020

Tang Dongfang, Zhao Yu Chen, Qian Danwen, Liu Hongliang, Luo Sheng, Patz Edward F, Moorman Patricia G, Su Li, Shen Sipeng, Christiani David C, Glass Carolyn, Gao Wen, Wei Qingyi

Abstract excerpt

The CREB-binding protein (CBP) pathway plays an important role in transcription and activity of acetyltransferase that acetylates lysine residues of histones and nonhistone proteins. In the present study, we hypothesized that genetic variants in the CBP pathway genes played a role in survival of non-small-cell lung cancer (NSCLC). We tested this hypothesis using the genotyping data from the genome-wide...

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Source

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Identifiers

PMID: 31713888
DOI: 10.1002/mc.23132
PMCID: PMC7481022

Genes

HDAC2
PPARGC1A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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