Article
Genome-wide association study of early-stage non-small cell lung cancer prognosis: a pooled analysis in the International Lung Cancer Consortium.
Carcinogenesis - 3 Apr 2025
Dong Mei, Thakral Abhinav, Byrne Karl Smith-, Bosse Yohan, Zhou Hufeng, Zhang Yi, Atkins Joshua, Haycock Philip, Brown M Catherine, Murison Kiera, Timens Wim, Sin Don D, Kothari Jui, Gabriel Aurélie A G, Zaridze David, Savic Milan, Lissowska Jolanta, Świątkowska Beata, Janout Vladimir, Holcatova Ivana, Mukeria Anush, Fernandez-Tardon Guillermo, Davies Michael P A, Triplette Matthew, Schabath Matthew B, Andrew Angeline S, Chen Chu, Taylor Fiona, Field John K, Tardon Adonina, Shete Sanjay S, Brennan Paul, Landi Maria Teresa, McKay James, Amos Christopher I, Lin Xihong, Christiani David C, Hung Rayjean J, Liu Geoffrey, Xu Wei
Abstract excerpt
Lung cancer is the leading cause of cancer mortality. To investigate genetic determinants for prognosis among patients diagnosed with early-stage non-small cell lung cancer (NSCLC), we conducted the first large-scale genome-wide association prognostic study using data from the International Lung Cancer Consortium (ILCCO) through a two-phase analysis. Phase 1 includes the discovery of genome-wide association...
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