Article
Optogenetically transduced human ES cell-derived neural progenitors and their neuronal progenies: Phenotypic characterization and responses to optical stimulation.
PloS one - 1 Jan 2019
Ryu Jiwon, Vincent Philippe F Y, Ziogas Nikolaos K, Xu Leyan, Sadeghpour Shirin, Curtin John, Alexandris Athanasios S, Stewart Nicholas, Sima Richard, du Lac Sascha, Glowatzki Elisabeth, Koliatsos Vassilis E
Abstract excerpt
Optogenetically engineered human neural progenitors (hNPs) are viewed as promising tools in regenerative neuroscience because they allow the testing of the ability of hNPs to integrate within nervous system of an appropriate host not only structurally, but also functionally based on the responses of their differentiated progenies to light. Here, we transduced H9 embryonic stem cell-derived hNPs with a lentivirus...
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