Article
Analytical Assessment of the Vela Diagnostics NGS Assay for HIV Genotyping and Resistance Testing: The Apulian Experience.
International journal of molecular sciences - 1 Mar 2022
Bonifacio Maria Addolorata, Genchi Chiara, Lagioia Antonella, Talamo Vincenza, Volpe Anna, Mariggiò Maria Addolorata
Abstract excerpt
Drug-resistance monitoring is one of the hardest challenges in HIV management. Next-generation sequencing (NGS) technologies speed up the detection of drug resistance, allowing the adjustment of antiretroviral therapy and enhancing the quality of life of people living with HIV. Recently, the NGS Sentosa® SQ HIV Genotyping Assay (Vela Diagnostics) received approval for in vitro diagnostics use. This work is the...
Topics
- Anti-HIV Agents
- Drug Resistance, Viral
- Genotype
- HIV Infections
- HIV-1
- High-Throughput Nucleotide Sequencing
- Humans
- Mutation
- Quality of Life
- RNA, Viral
