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Article

Lower LINE-1 methylation is associated with promoter hypermethylation and distinct molecular features in gastric cancer.

Epigenomics - 1 Nov 2019

Tahara Sayumi, Tahara Tomomitsu, Horiguchi Noriyuki, Okubo Masaaki, Terada Tsuyoshi, Yoshida Dai, Funasaka Kohei, Nakagawa Yoshihito, Shibata Tomoyuki, Tsukamoto Tetsuya, Ohmiya Naoki

Abstract excerpt

Aim: To investigate the associations between LINE1 methylation, an indicator for genome-wide hypomethylation, molecular and clinicopathological characteristics of gastric cancer (GC) patients. Patients & methods:LINE1 methylation statuses were examined in paired cancerous, non-neoplastic mucosa from 217 GC and gastric mucosa from separate group of 224 noncancer patients. CpG island methylator phenotype, TP53 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31701771
DOI: 10.2217/epi-2019-0091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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