Article
The accumulation of DNA demethylation in Sat α in normal gastric tissues with Helicobacter pylori infection renders susceptibility to gastric cancer in some individuals.
Oncology reports - 1 Jun 2012
Saito Masaaki, Suzuki Koichi, Maeda Takafumi, Kato Takaharu, Kamiyama Hidenori, Koizumi Kei, Miyaki Yuichiro, Okada Shinichiro, Kiyozaki Hirokazu, Konishi Fumio
Abstract excerpt
Helicobacter pylori (HP) infection is widely recognized as a risk factor for gastric cancer, but only a minority of infected individuals develop gastric cancer. The aim of this study was to determine whether DNA demethylation in non-cancerous gastric mucosa (NGM) significantly enhances susceptibility to gastric cancer. A total of 165 healthy volunteers, including 83...
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