Article
In vitro knock-out of miR-155 suppresses leukemic and HCV virus loads in pediatric HCV-4-associated acute lymphoid leukemia: A promising target therapy.
Journal of cellular biochemistry - 1 Apr 2020
Hassan Safaa S, El-Khazragy Nashwa, Elshimy Amal A, Aboelhussein Marwa M, Saleh Shereen A, Fadel Sayed, Atia Hend A, Matbouly Safa, Tamer Natalie
Abstract excerpt
Hepatitis C virus (HCV) infection is a major public health problem, having a high prevalence in Egypt. Leukemia and lymphoma have been associated with HCV infection. MicroRNA-155 (miR-155) has been reported to play a regulatory role in cancer, inflammation, and immune response to infection. The expression level of miR-155 in HCV viremic patients is controversial; although high miR-155 levels were demonstrated in...
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