Article
miRNA‐155 and miRNA‐181a as prognostic biomarkers for pediatric acute lymphoblastic leukemia
25 Oct 2018
Abstract excerpt
Mortality rates of acute lymphoblastic leukemia (ALL) have improved over the past 20 years; however, a significant portion of deaths stems from the lack of prognostic biomarkers, which can direct therapy and overcome drug resistance. microRNA-155a (miRNA-155a) and miRNA-181a are two single-stranded miRNAs involved in the pathogenesis of many types of leukemia and lymphoma and is linked to drug resistance. We...
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