Article
Expression of miR-652-3p and Effect on Apoptosis and Drug Sensitivity in Pediatric Acute Lymphoblastic Leukemia.
BioMed research international - 1 Jan 2018
Jiang Qian, Lu Xiaojing, Huang Pengli, Gao Chao, Zhao Xiaoxi, Xing Tianyu, Li Gang, Bao Shilai, Zheng Huyong
Abstract excerpt
MicroRNAs (miRNAs) expression profiles were screened in plasma samples from pediatric patients with acute lymphoblastic leukemia (ALL) and healthy controls, using qRT-PCR-based TaqMan low-density miRNA arrays. MiR-652-3p (a circulating miRNA) was downregulated in new diagnosis (ND) patients compared with healthy controls. The levels of miR652-3p were restored in complete remission (CR) but were downregulated...
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