The Apoptosis Pathway and CASP8 Variants Conferring Risk for Acute and Overuse Musculoskeletal Injuries.

doi:10.1002/jor.24504

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Article

The Apoptosis Pathway and CASP8 Variants Conferring Risk for Acute and Overuse Musculoskeletal Injuries.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Mar 2020

Seale Kirsten, Burger Marilize, Posthumus Michael, Häger Charlotte K, Stattin Evalena, Nilsson Kjell G, Collins Malcolm, September Alison V

Abstract excerpt

Rotator cuff tendinopathy (RCT), anterior cruciate ligament (ACL) ruptures, and carpal tunnel syndrome (CTS), are examples of chronic (RCT and CTS) and acute (ACL ruptures) musculoskeletal soft tissue injuries. These injuries are multifactorial in nature, with several identified intrinsic and extrinsic risk factors. Previous studies have implicated specific sequence variants within genes encoding structural and...

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PMID: 31692049
DOI: 10.1002/jor.24504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.