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Article

Modulators of the extracellular matrix and risk of anterior cruciate ligament ruptures.

Journal of science and medicine in sport - 1 Feb 2017

Rahim Masouda, Mannion Sasha, Klug Blake, Hobbs Hayden, van der Merwe Willem, Posthumus Michael, Collins Malcolm, September Alison V

Abstract excerpt

OBJECTIVES: The extracellular matrix (ECM) of ligaments continuously undergoes remodelling in order to maintain tissue homeostasis. Several key mediators of ECM remodelling were chosen for investigation in the present study. It is thought that polymorphisms within genes encoding signalling molecules may contribute to inter-individual variation in the responses to mechanical loading, potentially altering risk of...

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Source

Identifiers

PMID: 27720349
DOI: 10.1016/j.jsams.2016.07.003

Genes

CASP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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