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Article

Association between functional polymorphisms in the promoter of the miR-143/145 cluster and risk of conotruncal heart defects.

Personalized medicine - 1 Nov 2019

Wen Heling, Zhang Rui, Li Yajiao, Qian Hong, Yan Zhiguo, Chen Yu, Li Gang

Abstract excerpt

Aim: Conotruncal heart defects (CTDs) are the most common form of congenital heart disease. We investigated the association of these two single-nucleotide polymorphisms (SNPs) in the promoter of miR-143/145 (rs353292 and rs4705343) with the susceptibility to CTDs in a Chinese population. Materials & methods: Two SNPs in the promoter of miR-143/145 (rs353292 and rs4705343) have been examined by PCR-RFLP...

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Source

Identifiers

PMID: 31691635
DOI: 10.2217/pme-2018-0154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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