Article
No association of pri-miR-143 rs41291957 polymorphism with the risk of congenital heart disease in a Chinese population.
Pediatric cardiology - 1 Aug 2014
Yang Liping, Gao Xiaobo, Luo Haiyan, Huang Qiuyu, Wei Ying, Zhang Guican, Huang Guoying, Su Dongmei, Chen Liangwan, Lu Cailing, Yang Juhua, Ma Xu
Abstract excerpt
MiR-143 plays an important role in the heart development of zebra fish. The rs41291957 variant located in the pri-miR-143 sequence is associated with colorectal carcinogenesis. Therefore, the authors hypothesized that rs41291957 in pri-miR-143 might be involved in the risk of sporadic congenital heart disease (CHD). The authors conducted a case-control study of CHD in a Chinese population to test their hypothesis...
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