Article
Association Between miR-143/145 rs4705343 Polymorphism and Risk of Congenital Heart Disease in a Chinese Tibetan Population.
Genetic testing and molecular biomarkers - 1 Dec 2021
Qi Shenggui, Wang Chunyan, Li Li, Li Tengyan, Chen Qiuhong, Wang Jing
Abstract excerpt
Objective: Congenital heart disease (CHD) is the most common birth defect worldwide and is caused by both genetic and environmental factors. The microRNA (miR)-143/145 cluster is involved in various biological processes related to cardiovascular development. The functional single nucleotide polymorphism (SNP) rs4705343 of miR-143/145 may influence the expression of these miRNAs. In this study, we aimed to...
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