Article
Association between functional polymorphisms in the promoter of the miR-143/145 cluster and risk of intracranial aneurysm.
Scientific reports - 8 Mar 2017
Sima Xiutian, Sun Hong, Zhou Peizhi, You Chao, Cai Bowen
Abstract excerpt
MicroRNAs (miRs)-143/145 are involved in various biological processes related to aneurysm formation and are downregulated in patients with intracranial aneurysm (IA). We aimed to determine whether two functional polymorphisms (i.e. rs4705342 and rs4705343) in the promoter of miR-143/145 are related to IA risk. A case-control study was undertaken to examine the association of rs4705342 and rs4705343 with IA risk,...
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