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Article

Functional miR143/145 Cluster Variants and Haplotypes Are Associated with Chronic Kidney Disease: a Preliminary Case-Control Study and Computational Analyses.

Applied biochemistry and biotechnology - 1 May 2021

Sargazi Saman, Heidari Nia Milad, Mirani Sargazi Fariba, Sheervalilou Roghayeh, Saravani Ramin, Bahrami Sara, Mirinejad Shekoufeh, Alidadi Ali

Abstract excerpt

MiR-143/145 cluster is a novel transcriptional target of many signaling pathways, with variations within this cluster contributed to the risk of multiple diseases. To date, no data regarding the link between miR143/145 cluster polymorphisms and the risk of developing chronic kidney disease (CKD) has been reported. Hence, we aimed to examine such association in a population of Iranian ancestry. In this preliminary...

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PMID: 33484447
DOI: 10.1007/s12010-021-03489-w

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