Article
A polymorphism rs4705341 in the flanking region of miR-143/145 predicts risk and prognosis of colorectal cancer.
Oncotarget - 20 Sept 2016
Sun Ruifen, Chen Peng, Li Lijuan, Sun Hong, Nie Xinwen, Liang Yundan, Yuan Fang, Pu Yan, Bai Peng, Zhang Lin, Gao Linbo
Abstract excerpt
The aim of this study was to investigate the effect of a polymorphism rs4705341 in the flanking region of miR-143/145 on the risk of colorectal cancer (CRC). The rs4705341 polymorphism was analyzed in 1002 cases and 1062 controls using a polymerase chain reaction-restriction fragment length polymorphism method. We found a significantly reduced CRC susceptibility with miR-143/145 rs4705341 in homozygote comparison...
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