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Article

Association between polymorphisms in the promoter region of miR-143/145 and risk of colorectal cancer.

Human immunology - 1 Aug 2013

Li Lijuan, Pan Xinmin, Li Zhaohui, Bai Peng, Jin Hong, Wang Tao, Song Changping, Zhang Lin, Gao Linbo

Abstract excerpt

Emerging evidence suggests that down-regulated miRNAs play an important role in the carcinogenesis of colorectal cancer (CRC). Single nucleotide polymorphisms (SNPs) in the promoter region of miRNAs may disturb miRNAs processing, alter their expression, and ultimately affect an individual's susceptibility to CRC. We conducted a case-control study and analyzed twelve SNPs in the promoter region of miR-143/145 of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23628392
DOI: 10.1016/j.humimm.2013.04.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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