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STAT4 Gene Variant rs7574865 Is Associated with Rheumatoid Arthritis Activity and Anti-CCP Levels in the Western but Not in the Southern Population of Mexico.

Genes - 14 Feb 2024

Bravo-Villagra Karla Mayela, Muñoz-Valle José Francisco, Baños-Hernández Christian Johana, Cerpa-Cruz Sergio, Navarro-Zarza José Eduardo, Parra-Rojas Isela, Aguilar-Velázquez José Alonso, García-Arellano Samuel, López-Quintero Andres

Abstract excerpt

Rheumatoid Arthritis (RA) is a multifactorial autoimmune disease. Currently, several genes play an important role in the development of the disease. The objective was to evaluate the association of the STAT4 rs7574865 and rs897200 gene variants with RA susceptibility, DAS28, RF, and anti-CCP in Western and Southern Mexico populations. Genotyping was performed on 476 samples (cases = 240; controls = 236) using the...

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Identifiers

PMID: 38397230
DOI: 10.3390/genes15020241
PMCID: PMC10887563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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