Article
Single Nucleotide Polymorphism rs 2476601 of PTPN22 Gene and Susceptibility to Rheumatoid Arthritis in Iranian Population.
Iranian journal of allergy, asthma, and immunology - 1 Aug 2015
Ahmadloo Somayeh, Taghizadeh Mohsen, Akhiani Mohsen, Salimzadeh Ahmad, Keramatipour Mohammad
Abstract excerpt
The rs2476601 (R620W, C1858T) polymorphism in PTPN22 gene has been repeatedly reported to be associated with rheumatoid arthritis (RA). The rs 2476601 is widely suggested for predictive testing and risk assessment for RA. The aim of this study was to test the possible association of this SNP with RA in Iranian population. A total of 872 samples (405 confirmed RA patients and 467 healthy controls) were recruited...
Topics
- Arthritis, Rheumatoid
- Genetic Predisposition to Disease
- Genotype
- Humans
- Polymorphism, Single Nucleotide
- Protein Tyrosine Phosphatase, Non-Receptor Type 22
