Article
Total Gastrectomy for CDH-1 Mutation Carriers: An Institutional Experience.
The Journal of surgical research - 1 Mar 2020
DiBrito Sandra R, Blair Alex B, Prasath Vishnu, Habibi Mehran, Harmon John W, Duncan Mark D
Abstract excerpt
BACKGROUND: Gastric cancer is a leading cause of cancer-related death across the world. A subset of gastric cancers demonstrates an inherited genetic predisposition. Individuals with germline mutations in the CDH1 gene incur a lifetime risk for diffuse gastric cancer and benefit from prophylactic gastrectomy. The results for this operative intervention remain relatively undescribed in the literature, despite...
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