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Article

Identification of two unique naturally occurring Vpr sequence polymorphisms associated with clinical parameters in HIV-1 chronic infection.

Journal of medical virology - 1 Jan 2017

Kamori Doreen, Hasan Zafrul, Ohashi Jun, Kawana-Tachikawa Ai, Gatanaga Hiroyuki, Oka Shinichi, Ueno Takamasa

Abstract excerpt

HIV-1 viral protein R (Vpr) plays important roles in HIV-1 replication. Despite the identification of a number of HLA class I-associated immune escape mutations; it is yet known whether immune-driven Vpr polymorphisms are associated with disease outcome. Hereby, we comprehensively analyzed Vpr sequence polymorphisms and their association with disease outcome and host HLA genotypes, by using plasma viral RNA...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to vpr Gene Products, Human Immunodeficiency Virus

Source

Identifiers

PMID: 27328918
DOI: 10.1002/jmv.24612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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