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Article

Dissecting the dynamics of HIV-1 protein sequence diversity.

PloS one - 1 Jan 2013

Hu Yongli, Tan Paul ThiamJoo, Tan Tin Wee, August J Thomas, Khan Asif M

Abstract excerpt

The rapid mutation of human immunodeficiency virus-type 1 (HIV-1) and the limited characterization of the composition and incidence of the variant population are major obstacles to the development of an effective HIV-1 vaccine. This issue was addressed by a comprehensive analysis of over 58,000 clade B HIV-1 protein sequences reported over at least 26 years. The sequences were aligned and the 2,874 overlapping...

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Share to Amino Acid Motifs
Share to Databases, Genetic
Share to env Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to gag Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 23593157
DOI: 10.1371/journal.pone.0059994
PMCID: PMC3617185

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