Keratinocyte-intrinsic MHCII expression controls microbiota-induced Th1 cell responses

Abstract excerpt

The cross-talk between the microbiota and the immune system plays a fundamental role in the control of host physiology. However, the tissue-specific factors controlling this dialogue remain poorly understood. Here we demonstrate that T cell responses to commensal colonization are associated with the development of organized cellular clusters within the skin epithelium. These organized lymphocyte clusters are...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Dermatology and Skin Diseases
• Share to IL-33, ST2, and ILC Pathways
• Share to Immune Cell Function and Interaction