Article
Adaptive immunity to murine skin commensals.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jul 2014
Shen Wei, Li Wenqing, Hixon Julie A, Bouladoux Nicolas, Belkaid Yasmine, Dzutzev Amiran, Durum Scott K
Abstract excerpt
The adaptive immune system provides critical defense against pathogenic bacteria. Commensal bacteria have begun to receive much attention in recent years, especially in the gut where there is growing evidence of complex interactions with the adaptive immune system. In the present study, we observed that commensal skin bacteria are recognized by major populations of T cells in skin-draining lymph nodes of mice....
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