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γδ T cells respond directly and selectively to the skin commensal yeast <i>Malassezia</i> for IL-17-dependent fungal control

2023-09-12

Abstract excerpt

<h4>ABSTRACT</h4> Stable microbial colonization of the skin depends on tight control by the host immune system. The lipid-dependent yeast Malassezia typically colonizes skin as a harmless commensal and is subject to host type 17 immunosurveillance, but this fungus has also been associated with diverse skin pathologies in both humans and animals. Using a murine model of Malassezia exposure, we show that Vγ4 + d...

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Literature Corpus work
211dc5ed-8617-5aca-af2b-89da6ab9de83
DOI
10.1101/2023.09.08.556784
Open publication

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γδ T cells respond directly and selectively to the skin commensal yeast <i>Malassezia</i> for IL-17-dependent fungal controlDOI 10.1101/2023.09.08.556784
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