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Article

Genetic variability and functional implication of HPV16 from cervical intraepithelial neoplasia in Shanghai women.

Journal of medical virology - 1 Mar 2020

Zhao Junwei, Zhu Jiacheng, Guo Junhan, Zhu Tailin, Zhong Jixing, Liu Min, Ruan Yetian, Liao Shujie, Li Fang

Abstract excerpt

Human papillomavirus (HPV)16 gene mutation is usually associated with persistent HPV infection and cervical intraepithelial neoplasia (CIN). However, the functional implications of HPV16 mutations remain poorly understood.145 LCR/E6/E7 of the HPV16 isolates were amplified and sequenced, and HPV16 integration status was detected. In total, 89 SNPs (68 in the LCR, 13 in E6, 8 in E7) were discovered, 11 of which...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31670402
DOI: 10.1002/jmv.25618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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