Human papillomavirus (HPV) 18 genetic variants and cervical cancer risk in Taizhou area, China.

doi:10.1016/j.gene.2018.01.037

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Article

Human papillomavirus (HPV) 18 genetic variants and cervical cancer risk in Taizhou area, China.

Gene - 20 Mar 2018

Xu Hui-Hui, Zheng Ling-Zhi, Lin Ai-Fen, Dong Shan-Shan, Chai Ze-Ying, Yan Wei-Hua

Abstract excerpt

Human papillomavirus (HPV) type 18 is predominantly associated with the development of cervical adenocarcinomas, whereas data on HPV18 genetic variability in China are limited. HPV18 genetic variants were formed phylogenetic tree, including lineages A, B, and C. We aimed to evaluate the diversity of HPV18 genetic variants by sequencing the entire E6, E7 and L1 genes. Between 2012 and 2015, a total of 138 (0.8%,...

Topics

Adenocarcinoma
Adolescent
Adult
Aged
Aged, 80 and over
Capsid Proteins
China
Female
Genetic Variation
Genotype
Human papillomavirus 18
Humans
Middle Aged
Oncogene Proteins, Viral
Papillomavirus E7 Proteins
Papillomavirus Infections
Risk
Uterine Cervical Neoplasms

Source

Open in PubMed

Identifiers

PMID: 29331480
DOI: 10.1016/j.gene.2018.01.037

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