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Article

The difference of transcriptome of HPV-infected patients contributes more to the occurrence of cervical cancer than the mutations of E6 and E7 genes in HPV16.

Medicine - 19 Jan 2024

Zhang Lihui, Li Mengyuan, Yuan Feiyan, Jiang Jingyuan, Zhang Xinmin

Abstract excerpt

Human papillomavirus (HPV) E6 and E7 genes are biomarkers and drivers of the progression of cervical cancer (CxCa). The aim of this study was to investigate the relationship between HPV16 E6, E7 gene mutations and the occurrence and development of CxCa. Cervical exfoliated cells and clinical data of patients with cervical diseases were collected. Sample DNA was extracted, the E6 and E7 gene fragments were...

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Share to Human papillomavirus 16
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Oncogene Proteins, Viral

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Share to Uterine Cervical Neoplasms

Source

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Identifiers

PMID: 38241590
DOI: 10.1097/MD.0000000000036822
PMCID: PMC10798708

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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