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Genetic variability of the HPV16 early genes and LCR. Present and future perspectives

1 Jan 2021

Abstract excerpt

Human papillomavirus 16 (HPV16) infection is the aetiologic factor for the development of cervical dysplasia and is regarded as highly carcinogen, because it is implicated in more than 50% of cervical cancer cases, worldwide. The tumourigenic potential of HPV16 has triggered the extensive sequence analysis of viral genome in order to identify nucleotide variations and amino acid substitutions that influence viral...

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PMID: 34847982
DOI: 10.1017/erm.2021.18

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