Article
Impact of Higher Cell-Free DNA Yields on Liquid Biopsy Testing in Glioblastoma Patients
1 Jan 2025
Abstract excerpt
BACKGROUND: Minimally invasive molecular profiling using cell-free DNA (cfDNA) is increasingly important to the management of cancer patients; however, low sensitivity remains a major limitation, particularly for brain tumor patients. Transiently attenuating cfDNA clearance from the body-thereby, allowing more cfDNA to be sampled-has been proposed to improve the performance of liquid biopsy diagnostics. However,...
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