Article

Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors

2024-11-12

Abstract excerpt

A DNA sequence pattern, or “motif”, is an essential representation of DNA-binding specificity of a transcription factor (TF). Any particular motif model has potential flaws due to shortcomings of the underlying experimental data and computational motif discovery algorithm. As a part of the Codebook/GRECO-BIT initiative, here we evaluated at large scale the cross-platform recognition performance of positional weigh...

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Literature Corpus work: aa711579-9eef-51e0-aa82-087a9c583877
DOI: 10.1101/2024.11.11.619379

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