Article
Identification of IDH and TERTp mutation status using 1 H-MRS in 112 hemispheric diffuse gliomas.
Journal of magnetic resonance imaging : JMRI - 1 Jun 2020
Ozturk-Isik Esin, Cengiz Sevim, Ozcan Alpay, Yakicier Cengiz, Ersen Danyeli Ayca, Pamir M Necmettin, Özduman Koray, Dincer Alp
Abstract excerpt
BACKGROUND: There is a growing interest in noninvasively defining molecular subsets of hemispheric diffuse gliomas based on the isocitrate dehydrogenase (IDH) and telomerase reverse transcriptase gene promoter (TERTp) mutation status, which correspond to distinct tumor entities, and differ in demographics, natural history, treatment response, recurrence, and survival patterns. PURPOSE: To investigate whether...
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