Article
Radiomic study on preoperative multi-modal magnetic resonance images identifies IDH-mutant TERT promoter-mutant gliomas.
Cancer medicine - 1 Feb 2023
Wang Haoyu, Zhang Shuxin, Xing Xiang, Yue Qiang, Feng Wentao, Chen Siliang, Zhang Jun, Xie Dan, Chen Ni, Liu Yanhui
Abstract excerpt
OBJECTIVES: Gliomas with comutations of isocitrate dehydrogenase (IDH) genes and telomerase reverse transcriptase (TERT) gene promoter (IDHmut pTERTmut) show distinct biological features and respond to first-line treatment differently in comparison with other gliomas. This study aimed to characterize the IDHmut pTERTmut gliomas in multimodal MRI using the radiomic method and establish a precise diagnostic model...
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