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Article

Multicenter validation of amide proton transfer imaging for the classification of adult-type diffuse gliomas.

Magnetic resonance imaging - 1 Apr 2026

Jiang Tongling, Wu Minghao, Hu Junjiao, Guo Hu, Ma Xiaoyue, Liu Yaou, Zhang Yi

Abstract excerpt

Accurate classification of adult-type diffuse gliomas is essential for treatment planning, particularly following the 2021 WHO classification update. While amide proton transfer (APT) imaging shows promise, multicenter validation is needed to establish its clinical utility. This study aims to evaluate the multicenter performance of the APT-weighted (APTw) metric for differentiating genotypes, grades, and subtypes...

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PMID: 41453459
DOI: 10.1016/j.mri.2025.110599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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