Noncontrast Magnetic Resonance Fingerprinting-Habitat Framework for Intratumoral Heterogeneity Decoding and Isocitrate Dehydrogenase Mutation Prediction in Diffuse Gliomas.

doi:10.1200/PO-26-00243

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Article

Noncontrast Magnetic Resonance Fingerprinting-Habitat Framework for Intratumoral Heterogeneity Decoding and Isocitrate Dehydrogenase Mutation Prediction in Diffuse Gliomas.

JCO precision oncology - 1 Sept 2026

Song Dandan, Li Borui, Liu Yan, Guo Peixu, Mi Yaqin, Yang Binju, Qu Haiyuan, Jiang Yueluan, Song Yang, Zhang Chengxiu, Yang Guang, Fan Guoguang, Chang Miao

Abstract excerpt

PURPOSE: To develop and validate a magnetic resonance fingerprinting (MRF)-based habitat imaging framework for noninvasively decoding intratumoral heterogeneity (ITH) and preoperatively predicting isocitrate dehydrogenase (IDH) mutation status in diffuse gliomas. MATERIALS AND METHODS: In this prospective study (January 2024-September 2025), 141 adults with diffuse gliomas (56 IDH-mutant, 85 IDH-wildtype) were...

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Topics

Humans
Isocitrate Dehydrogenase
Glioma
Brain Neoplasms
Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Magnetic Resonance Imaging

Prospective Studies

Male

Adult

Middle Aged

Radiomics

Prognosis

Source

Open in PubMed

Identifiers

PMID: 42777176
DOI: 10.1200/PO-26-00243

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