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Article

Detecting IDH and TERTp mutations in diffuse gliomas using 1H-MRS with attention deep-shallow networks.

Computers in biology and medicine - 1 Mar 2025

Sacli-Bilmez Banu, Bas Abdullah, Erşen Danyeli Ayça, Yakicier M Cengiz, Pamir M Necmettin, Özduman Koray, Dinçer Alp, Ozturk-Isik Esin

Abstract excerpt

BACKGROUND: Preoperative and noninvasive detection of isocitrate dehydrogenase (IDH) and telomerase reverse transcriptase gene promoter (TERTp) mutations in glioma is critical for prognosis and treatment planning. This study aims to develop deep learning classifiers to identify IDH and TERTp mutations using proton magnetic resonance spectroscopy (1H-MRS) and a one-dimensional convolutional neural network (1D-CNN)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39874812
DOI: 10.1016/j.compbiomed.2025.109736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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