Article

Charge-based fingerprinting of unlabeled full-length proteins using an aerolysin nanopore

2025-01-16

Abstract excerpt

Proteins play essential roles in cellular processes and are involved in numerous diseases, driving the need for efficient proteoform identification. While nanopore technology was highly successful for DNA sequencing, this approach has not yet delivered its full potential in protein identification. Here, we demonstrate the capabilities of an aerolysin nanopore for direct identification of a range of unlabeled full-...

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Literature Corpus work: 1a0b0da9-9f38-5e47-8753-bc3dde997077
DOI: 10.1101/2025.01.13.632743

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