Article
Human leukocyte antigen (HLA) diversity and clinical applications in South Africa.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde - 10 Sept 2019
Mellet J, Tshabalala M, Agbedare O, Meyer Pwa, Gray C M, Pepper M S
Abstract excerpt
The major histocompatibility complex, known as the human leukocyte antigen (HLA) complex in humans, forms an integral component of adaptive T cell immunity by presenting self and non-self peptides to the T cell receptor, thereby allowing clonal expansion of responding peptide-specific CD4+ and CD8+ T cells. HLA likewise forms an integral part of the innate immune response through the binding of killer-cell...
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