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HLA major allele group frequencies in a diverse population of the Free State Province, South Africa

1 Apr 2021

Abstract excerpt

BACKGROUND: Human Leucocyte Antigens (HLA) play a vital role in disease pathogenesis and transplant rejection. HLA-typing is a useful tool in predicting disease progression and to identify potential organ donors. Due to human migration and known ethnic variation, frequent targeted HLA sequencing of specific populations is crucial to increase their representation in global reference panels. MATERIALS AND METHODS:...

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PMID: 33981900
DOI: 10.1016/j.heliyon.2021.e06850

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