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Article

β-Klotho gene variation is associated with liver damage in children with NAFLD.

Journal of hepatology - 1 Mar 2020

Dongiovanni Paola, Crudele Annalisa, Panera Nadia, Romito Ilaria, Meroni Marica, De Stefanis Cristiano, Palma Alessia, Comparcola Donatella, Fracanzani Anna Ludovica, Miele Luca, Valenti Luca, Nobili Valerio, Alisi Anna

Abstract excerpt

BACKGROUND & AIM: Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in adults and children. Along with obesity, diabetes and insulin resistance, genetic factors strongly impact on NAFLD development and progression. Dysregulated bile acid metabolism and the fibroblast growth factor 19 (FGF19) pathway play a pivotal role in NAFLD pathogenesis. However, the mechanism through...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 31655133
DOI: 10.1016/j.jhep.2019.10.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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