Article
Oxidized fatty acids: A potential pathogenic link between fatty liver and type 2 diabetes in obese adolescents?
Antioxidants & redox signaling - 10 Jan 2014
Santoro Nicola, Caprio Sonia, Giannini Cosimo, Kim Grace, Kursawe Romy, Pierpont Bridget, Shaw Melissa M, Feldstein Ariel E
Abstract excerpt
In this study, we sought to investigate the putative association of the oxidized metabolites derived from linoleic acid (OXFAs) with pediatric nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D). We studied 80 obese adolescents (age 13.3 ± 3.31 years; body mass index 33.0 ± 6.79 kg/m(2)), who underwent an oral glucose tolerance test, a magnetic resonance imaging (MRI) to measure the hepatic fat...
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