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Article

Association of MTTP gene variants with pediatric NAFLD: A candidate-gene-based analysis of single nucleotide variations in obese children.

PloS one - 1 Jan 2017

Dai Dongling, Wen Feiqiu, Zhou Shaoming, Su Zhe, Liu Guosheng, Wang Mingbang, Zhou Jianli, He Fusheng

Abstract excerpt

OBJECTIVE: We used targeted next-generation sequencing to investigate whether genetic variants of lipid metabolism-related genes are associated with increased susceptibility to nonalcoholic fatty liver disease (NAFLD) in obese children. METHODS: A cohort of 100 obese children aged 6 to 18 years were divided into NAFLD and non-NAFLD groups and subjected to hepatic ultrasound, anthropometric, and biochemical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28953935
DOI: 10.1371/journal.pone.0185396
PMCID: PMC5617203

Genes

MTTP

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